Glial progenitor-like phenotype in low-grade glioma and enhanced CD133-expression and neuronal lineage differentiation potential in high-grade glioma.

While neurosphere- as well as xenograft tumor-initiating cells have been identified in gliomas, the resemblance between glioma cells and neural stem/progenitor cells as well as the prognostic value of stem/progenitor cell marker expression in glioma are poorly clarified.Viable glioma cells were char...

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Bibliographic Details
Main Authors: Johan Rebetz, Dongping Tian, Annette Persson, Bengt Widegren, Leif G Salford, Elisabet Englund, David Gisselsson, Xiaolong Fan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-04-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2277459?pdf=render