Independent role of caspases and Bik in augmenting influenza A virus replication in airway epithelial cells and mice

Independent role of caspases and Bik in augmenting influenza A virus replication in airway epithelial cells and mice

Abstract Caspases and poly (ADP-ribose) polymerase 1 (PARP1) have been shown to promote influenza A virus (IAV) replication. However, the relative importance and molecular mechanisms of specific caspases and their downstream substrate PARP1 in regulating viral replication in airway epithelial cells...

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Bibliographic Details
Main Authors: Sourabh Soni, Stephanie Walton-Filipczak, Richard S. Nho, Yohannes Tesfaigzi, Yohannes A. Mebratu
Format: Article
Language:English
Published: BMC 2023-04-01
Series:Virology Journal
Subjects:
Influenza A virus
Caspase
Q-VD-Oph
PARP1
Bik wild-type and knockout mice
Online Access:https://doi.org/10.1186/s12985-023-02027-w

Internet

https://doi.org/10.1186/s12985-023-02027-w

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