Attenuation of Polycyclic Aromatic Hydrocarbon (PAH)-Mediated Pulmonary DNA Adducts and Cytochrome P450 (CYP)1B1 by Dietary Antioxidants, Omega-3 Fatty Acids, in Mice

Attenuation of Polycyclic Aromatic Hydrocarbon (PAH)-Mediated Pulmonary DNA Adducts and Cytochrome P450 (CYP)1B1 by Dietary Antioxidants, Omega-3 Fatty Acids, in Mice

Numerous human and animal studies have reported positive correlation between carcinogen-DNA adduct levels and cancer occurrence. Therefore, attenuation of DNA adduct levels would be expected to suppress tumorigenesis. In this investigation, we report that the antioxidants omega 3-fatty acids, which...

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Bibliographic Details
Main Authors: Guodong Zhou, Weiwu Jiang, Guobin Xia, Lihua Wang, Molly Richardson, Chun Chu, Bhagavatula Moorthy
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Antioxidants
Subjects:
fish oil
eicosapentaenoic acid
docosahexaenoic
polycyclic aromatic hydrocarbons
DNA adducts
CYP1
Online Access:https://www.mdpi.com/2076-3921/11/1/119

Internet

https://www.mdpi.com/2076-3921/11/1/119

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