Expression of HIF-1α is related to a poor prognosis and tamoxifen resistance in contralateral breast cancer.

BACKGROUND:Adjuvant endocrine treatment improves survival after estrogen receptor (ER) positive breast cancer. Recurrences occur, and most patients with metastatic breast cancer develop treatment resistance and incurable disease. An influential factor in relation to endocrine treatment resistance is...

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Bibliographic Details
Main Authors: Annika Jögi, Anna Ehinger, Linda Hartman, Sara Alkner
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0226150