LY395756 promotes NR2B expression via activation of AKT/CREB signaling in the juvenile methylazoxymethanol mice model of schizophrenia

Abstract Introduction Synaptic N‐methyl‐d‐aspartate receptor subtype 2B(NR2B) is significantly reduced in prefrontal cortex (PFC) in the neurodevelopmental methylazoxymethanol (MAM) model of schizophrenia (SCZ). Recent research has shown that LY395756 can effectively restore NR2B levels and improve...

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Bibliographic Details
Main Authors: Meng‐lin Li, Yuan Peng, Ying An, Guo‐yan Li, Yue Lan
Format: Article
Language:English
Published: Wiley 2022-02-01
Series:Brain and Behavior
Subjects:
Online Access:https://doi.org/10.1002/brb3.2466