The Pharmacogenetics of Statin Therapy on Clinical Events: No Evidence that Genetic Variation Affects Statin Response on Myocardial Infarction

The Pharmacogenetics of Statin Therapy on Clinical Events: No Evidence that Genetic Variation Affects Statin Response on Myocardial Infarction

Background: The pharmacogenetic effect on cardiovascular disease reduction in response to statin treatment has only been assessed in small studies. In a pharmacogenetic genome wide association study (GWAS) analysis within the Genomic Investigation of Statin Therapy (GIST) consortium, we investigated...

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Bibliographic Details
Main Authors: Stella Trompet, Iris Postmus, Helen R. Warren, Raymond Noordam, Roelof A. J. Smit, Elizabeth Theusch, Xiaohui Li, Benoit Arsenault, Daniel I. Chasman, Graham A. Hitman, Patricia B. Munroe, Jerome I. Rotter, Bruce M. Psaty, Mark J. Caulfield, Ron M. Krauss, Adrienne L. Cupples, Wouter J. Jukema
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-01-01
Series:Frontiers in Pharmacology
Subjects:
pharmacogenetics
statins
GWAS
cardiovascular disease
myocardial infarction
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.679857/full

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https://www.frontiersin.org/articles/10.3389/fphar.2021.679857/full

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