A low dose adenovirus vectored vaccine expressing Schistosoma mansoni Cathepsin B protects from intestinal schistosomiasis in mice

A low dose adenovirus vectored vaccine expressing Schistosoma mansoni Cathepsin B protects from intestinal schistosomiasis in mice

Summary: Background: Schistosomiasis is an underestimated neglected tropical disease which affects over 236.6 million people worldwide. According to the CDC, the impact of this disease is second to only malaria as the most devastating parasitic infection. Affected individuals manifest chronic patho...

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Bibliographic Details
Main Authors: Dilhan J. Perera, Adam S. Hassan, Sunny S. Liu, Seyyed Mehdy Elahi, Christine Gadoury, Risini D. Weeratna, Rénald Gilbert, Momar Ndao
Format: Article
Language:English
Published: Elsevier 2022-06-01
Series:EBioMedicine
Subjects:
Schistosoma mansoni
Parasite
Vaccine
Viral vector
Schistosomiasis
Heterologous
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396422002171

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http://www.sciencedirect.com/science/article/pii/S2352396422002171

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