The mechanisms underlying the actions of Xuefu Zhuyu decoction pretreatment against neurological deficits after ischemic stroke in mice: The mediation of glymphatic function by aquaporin-4 and its anchoring proteins

The mechanisms underlying the actions of Xuefu Zhuyu decoction pretreatment against neurological deficits after ischemic stroke in mice: The mediation of glymphatic function by aquaporin-4 and its anchoring proteins

Ischemic stroke (IS) has been associated with an impairment in glymphatic function. Xuefu Zhuyu Decoction (XFZYD) is widely used in the prevention and treatment of ischemic stroke. We hypothesized that Xuefu Zhuyu decoction pretreatment could attenuate early neurological deficits after ischemic stro...

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Bibliographic Details
Main Authors: Ting Yi, Ping Gao, Meng Hou, Huan Lv, Mengyuan Huang, Shanshan Gao, Jinrong He, Dongdong Yang, Weiyin Chen, Tianmin Zhu, Chang Yu, Fuyou Liu, Haiyan Yin, Shuoguo Jin
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Pharmacology
Subjects:
ischemic stroke
Xuefu Zhuyu decoction
glymphatic system
neuroprotection
aquaporin-4
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.1053253/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2022.1053253/full

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