Automatic Optimization of an in Silico Model of Human iPSC Derived Cardiomyocytes Recapitulating Calcium Handling Abnormalities
The growing importance of human induced pluripotent stem cell-derived cardiomyoyctes (hiPSC-CMs), as patient-specific and disease-specific models for studying cellular cardiac electrophysiology or for preliminary cardiotoxicity tests, generated better understanding of hiPSC-CM biophysical mechanisms...
Hoofdauteurs: | , , , , , , |
---|---|
Formaat: | Artikel |
Taal: | English |
Gepubliceerd in: |
Frontiers Media S.A.
2018-06-01
|
Reeks: | Frontiers in Physiology |
Onderwerpen: | |
Online toegang: | https://www.frontiersin.org/article/10.3389/fphys.2018.00709/full |