Kinetic characteristics of transcriptional bursting in a complex gene model with cyclic promoter structure
While transcription often occurs in a bursty manner, various possible regulations can lead to complex promoter patterns such as promoter cycles, giving rise to an important question: How do promoter kinetics shape transcriptional bursting kinetics? Here we introduce and analyze a general model of th...
Main Authors: | , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
AIMS Press
2022-01-01
|
Series: | Mathematical Biosciences and Engineering |
Subjects: | |
Online Access: | https://www.aimspress.com/article/doi/10.3934/mbe.2022153?viewType=HTML |