Kinetic characteristics of transcriptional bursting in a complex gene model with cyclic promoter structure

While transcription often occurs in a bursty manner, various possible regulations can lead to complex promoter patterns such as promoter cycles, giving rise to an important question: How do promoter kinetics shape transcriptional bursting kinetics? Here we introduce and analyze a general model of th...

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Bibliographic Details
Main Authors: Xiyan Yang, Zihao Wang, Yahao Wu, Tianshou Zhou, Jiajun Zhang
Format: Article
Language:English
Published: AIMS Press 2022-01-01
Series:Mathematical Biosciences and Engineering
Subjects:
Online Access:https://www.aimspress.com/article/doi/10.3934/mbe.2022153?viewType=HTML