Endothelial Jagged-1 Is Necessary for Homeostatic and Regenerative Hematopoiesis

Endothelial Jagged-1 Is Necessary for Homeostatic and Regenerative Hematopoiesis

The bone marrow (BM) microenvironment is composed of multiple niche cells that, by producing paracrine factors, maintain and regenerate the hematopoietic stem cell (HSC) pool (Morrison and Spradling, 2008). We have previously demonstrated that endothelial cells support the proper regeneration of the...

Full description

Bibliographic Details
Main Authors: Michael G. Poulos, Peipei Guo, Natalie M. Kofler, Sandra Pinho, Michael C. Gutkin, Anastasia Tikhonova, Iannis Aifantis, Paul S. Frenette, Jan Kitajewski, Shahin Rafii, Jason M. Butler
Format: Article
Language:English
Published: Elsevier 2013-09-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124713004105

Internet

http://www.sciencedirect.com/science/article/pii/S2211124713004105

Similar Items