The Identification of Long Non-coding RNA H19 Target and Its Function in Chronic Myeloid Leukemia

H19 is a long non-coding RNA which was lowly expressed in chronic myeloid leukemia (CML). Here, we found that the overexpression of H19 significantly inhibited cell viability and colony formation and prolongs survival in CML cell lines and three xenografted mouse models. The H19 target proteins and...

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Bibliographic Details
Main Authors: Juhua Yang, Zhao Yin, Yumin Li, Yanjun Liu, Guiping Huang, Chunming Gu, Jia Fei
Format: Article
Language:English
Published: Elsevier 2020-03-01
Series:Molecular Therapy: Nucleic Acids
Online Access:http://www.sciencedirect.com/science/article/pii/S2162253120300561