Placental Hypomethylation Is More Pronounced in Genomic Loci Devoid of Retroelements

Placental Hypomethylation Is More Pronounced in Genomic Loci Devoid of Retroelements

The human placenta is hypomethylated compared to somatic tissues. However, the degree and specificity of placental hypomethylation across the genome is unclear. We assessed genome-wide methylation of the human placenta and compared it to that of the neutrophil, a representative homogeneous somatic c...

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Bibliographic Details
Main Authors: Aniruddha Chatterjee, Erin C. Macaulay, Euan J. Rodger, Peter A. Stockwell, Matthew F. Parry, Hester E. Roberts, Tania L. Slatter, Noelyn A. Hung, Celia J. Devenish, Ian M. Morison
Format: Article
Language:English
Published: Oxford University Press 2016-07-01
Series:G3: Genes, Genomes, Genetics
Subjects:
hypomethylation
placenta
neutrophil
retroelement
reduced representation bisulfite sequencing
Online Access:http://g3journal.org/lookup/doi/10.1534/g3.116.030379

Internet

http://g3journal.org/lookup/doi/10.1534/g3.116.030379

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