Human stem cell-derived GABAergic neurons functionally integrate into human neuronal networks
Abstract Gamma-aminobutyric acid (GABA)-releasing interneurons modulate neuronal network activity in the brain by inhibiting other neurons. The alteration or absence of these cells disrupts the balance between excitatory and inhibitory processes, leading to neurological disorders such as epilepsy. I...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2021-11-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-021-01270-x |