Design, Synthesis and Biological Evaluation of Novel Ketamine Derivatives as NMDAR Antagonists

Depression is a chronic, severe, and often life-threatening neurological disorder. It not only causes depression in patients and affects daily life but, in severe cases, may lead to suicidal behavior and have adverse effects on families and society. In recent years, it has been found that sub-anesth...

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Bibliographic Details
Main Authors: Shiyun Li, Bin Wen, Wei Zhao, Lulu Wang, Xingquan Chen
Format: Article
Language:English
Published: MDPI AG 2024-05-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/29/11/2459