Formononetin Promotes Cell Cycle Arrest via Downregulation of Akt/Cyclin D1/CDK4 in Human Prostate Cancer Cells

Background: Formononetin is an O-methylated isoflavone isolated from the root of Astragalus membranaceus. It has already been reported that formononetin could inhibit cell proliferation and induce cell apoptosis in several cancers, including prostate cancer. This study aimed to further investigate w...

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Bibliographic Details
Main Authors: Tianyu Li, Xinge Zhao, Zengnan Mo, Weihua Huang, Haibiao Yan, Zhian Ling, Yu Ye
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2014-10-01
Series:Cellular Physiology and Biochemistry
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Online Access:http://www.karger.com/Article/FullText/366342