HPLC-MS analysis of Schisandra lignans and their metabolites in Caco-2 cell monolayer and rat everted gut sac models and in rat plasma
The absorption profiles of Schisandra chinensis were evaluated using the human Caco-2 cell monolayer and rat everted gut sac models, as well as in rat plasma. By analyzing the chromatographic and MSn characteristics of individual peak acquired by HPLC-DAD-APCI-MSn determination, thirteen lignans wer...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2011-06-01
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Series: | Acta Pharmaceutica Sinica B |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2211383511000086 |