p27KIP1 Deletions in Childhood Acute Lymphoblastic Leukemia

p27KIP1 Deletions in Childhood Acute Lymphoblastic Leukemia

The p27KIP1 gene, which encodes a cyclin-dependent kinase (CDK) inhibitor, has been assigned to chromosome band 12p12, a region often affected by cytogenetically apparent deletions or translocations in childhood acute lymphoblastic leukemia (ALL). As described here, fluorescence in situ hybridizatio...

Full description

Bibliographic Details
Main Authors: Hiroaki Komuro, Marcus B. Valentine, Jeffrey E. Rubnitz, Midori Saito, Susana C. Raimondi, Andrew J. Carroll, Taolin Yi, Charles J. Sherr, A. Thomas Look
Format: Article
Language:English
Published: Elsevier 1999-08-01
Series:Neoplasia: An International Journal for Oncology Research
Subjects:
acute lymphoblastic leukemia
p27KIP1
cell cycle inhibitor
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558699800451

Internet

http://www.sciencedirect.com/science/article/pii/S1476558699800451

Similar Items