West Nile virus (WNV) replication is independent of autophagy in mammalian cells.

Autophagy is a homeostatic process responsible for recycling cytosolic proteins and organelles. Moreover, this pathway contributes to the cell's intrinsic innate defenses. While many viruses have evolved mechanisms to antagonize the antiviral effects of the autophagy pathway, others subvert aut...

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Bibliographic Details
Main Authors: Rianna Vandergaast, Brenda L Fredericksen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3448696?pdf=render