Phenotypic and genetic changes associated with the seesaw effect in MRSA strain N315 in a bioreactor model

Phenotypic and genetic changes associated with the seesaw effect in MRSA strain N315 in a bioreactor model

ABSTRACT: Objectives: Over the past decade, daptomycin treatment of methicillin-resistant Staphylococcus aureus (MRSA) infections has led to the emergence of daptomycin nonsusceptible (DAP-NS) MRSA strains and a subsequent interest in combinatorial antibiotic therapies. We investigated the phenotyp...

Full description

Bibliographic Details
Main Authors: Smruti Mishra, Erica Lasek-Nesselquist, Anarv Mathur, Zhuo Ma, Kanpong Boonthaworn, Nicholas O'Donnell, Haixin Sui, Janice D. Pata, Kathleen A. McDonough, Pradeepa Jayachandran, Meenakshi Malik
Format: Article
Language:English
Published: Elsevier 2022-03-01
Series:Journal of Global Antimicrobial Resistance
Subjects:
MRSA
Daptomycin nonsusceptibility
Seesaw effect
Cell wall thickness
Cell surface charge
Online Access:http://www.sciencedirect.com/science/article/pii/S2213716522000170

Internet

http://www.sciencedirect.com/science/article/pii/S2213716522000170

Similar Items