Complement-activating donor-specific anti-HLA antibodies in solid organ transplantation: systematic review, meta-analysis, and critical appraisal

Complement-activating donor-specific anti-HLA antibodies in solid organ transplantation: systematic review, meta-analysis, and critical appraisal

IntroductionSeveral studies have investigated the impact of circulating complement-activating anti-human leukocyte antigen donor-specific antibodies (anti-HLA DSAs) on organ transplant outcomes. However, a critical appraisal of these studies and a demonstration of the prognostic value of complement-...

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Bibliographic Details
Main Authors: Solaf Al-Awadhi, Marc Raynaud, Kevin Louis, Antoine Bouquegneau, Jean-Luc Taupin, Olivier Aubert, Alexandre Loupy, Carmen Lefaucheur
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-10-01
Series:Frontiers in Immunology
Subjects:
complement-activation
donor specific antibodies
anti-HLA
rejection
transplantation outcomes
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1265796/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1265796/full

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