Remodeling characteristics of H3K27me3-marked silencer in gastric intestinal metaplasia and its transcriptional regulatory mechanism

Remodeling characteristics of H3K27me3-marked silencer in gastric intestinal metaplasia and its transcriptional regulatory mechanism

Objective To systemically characterize the genome-wide distribution of H3K27me3-marked silencers in gastric intestinal metaplasia (IM) tissues and to elucidate a novel epigenetic regulatory mechanism of IM. Methods Gastric antrum mucosa samples were collected from 22 healthy individuals and 39 patie...

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Bibliographic Details
Main Authors: WU Linyu, LIU Wenkang, YU Bo, CHU Zhaole, LIU Biying
Format: Article
Language:zho
Published: Editorial Office of Journal of Army Medical University 2023-03-01
Series:陆军军医大学学报
Subjects:
intestinal metaplasia
epigenetics
histone modification h3k27me3
silencer
transcription factor
Online Access:http://aammt.tmmu.edu.cn/html/202210068.htm

Internet

http://aammt.tmmu.edu.cn/html/202210068.htm

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