GroupRank: rank candidate genes in PPI network by differentially expressed gene groups.

Many cell activities are organized as a network, and genes are clustered into co-expressed groups if they have the same or closely related biological function or they are co-regulated. In this study, based on an assumption that a strong candidate disease gene is more likely close to gene groups in w...

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Bibliographic Details
Main Authors: Qing Wang, Siyi Zhang, Shichao Pang, Menghuan Zhang, Bo Wang, Qi Liu, Jing Li
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4199715?pdf=render