SAR of Sponge-Inspired Hemibastadin Congeners Inhibiting Blue Mussel PhenolOxidase

SAR of Sponge-Inspired Hemibastadin Congeners Inhibiting Blue Mussel PhenolOxidase

Hemibastadin derivatives, including the synthetically-derived 5,5′-dibromohemibastadin-1 (DBHB), are potent inhibitors of blue mussel phenoloxidase (PO), which is a key enzyme involved in the firm attachment of this invertebrate to substrates and, thus, a promising molecular target for anti-fouling...

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Bibliographic Details
Main Authors: Hendrik Niemann, Jens Hagenow, Mi-Young Chung, Claire Hellio, Horst Weber, Peter Proksch
Format: Article
Language:English
Published: MDPI AG 2015-05-01
Series:Marine Drugs
Subjects:
antifouling
hemibastadin
phenoloxidase
sponges
copper
Mytilus edulis
Online Access:http://www.mdpi.com/1660-3397/13/5/3061

Internet

http://www.mdpi.com/1660-3397/13/5/3061

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