ESRP1-driven alternative splicing of CLSTN1 inhibits the metastasis of gastric cancer

Abstract Tumor metastasis severely limits the prognosis of gastric cancer patients. RNA-binding proteins (RBPs) are crucial in tumor metastasis, yet there is limited research into their involvement in gastric cancer. Here, we found that ESRP1, a RBP specific in epithelial cells, is important in regu...

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Bibliographic Details
Main Authors: Chengguo Li, Yuping Yin, Ruikang Tao, Yao Lin, Tao Wang, Qian Shen, Runze Li, Kaixiong Tao, Weizhen Liu
Format: Article
Language:English
Published: Nature Publishing Group 2023-12-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-023-01757-8