Population FBA predicts metabolic phenotypes in yeast.

Using protein counts sampled from single cell proteomics distributions to constrain fluxes through a genome-scale model of metabolism, Population flux balance analysis (Population FBA) successfully described metabolic heterogeneity in a population of independent Escherichia coli cells growing in a d...

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Bibliographic Details
Main Authors: Piyush Labhsetwar, Marcelo C R Melo, John A Cole, Zaida Luthey-Schulten
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-09-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC5626512?pdf=render