Cytoskeleton Dependent Mobility Dynamics of FcγRIIA Facilitates Platelet Haptotaxis and Capture of Opsonized Bacteria

Platelet adhesion and spreading at the sites of vascular injury is vital to hemostasis. As an integral part of the innate immune system, platelets interact with opsonized bacterial pathogens through FcγRIIA and contribute to host defense. As mechanoscavangers, platelets actively migrate and capture...

Full description

Bibliographic Details
Main Authors: Raghavendra Palankar, Laura Sachs, Jan Wesche, Andreas Greinacher
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/11/10/1615