Effect and Mechanism of Si-Miao-Yong-An on Vasa Vasorum Remodeling in ApoE−/− Mice with Atherosclerosis Vulnerable Plague

Effect and Mechanism of Si-Miao-Yong-An on Vasa Vasorum Remodeling in ApoE−/− Mice with Atherosclerosis Vulnerable Plague

Objective: To observe the effect of Si-Miao-Yong-An (SMYA) on atherosclerosis (AS) vulnerable plaques, and to further explore the mechanism by vasa vasorum (VV) angiogenesis and maturation as an entry point.Methods: SPF-class healthy male ApoE−/− mice were randomized into model group, simvastatin gr...

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Bibliographic Details
Main Authors: Meng Li, Zhongwen Qi, Junping Zhang, Ke Zhu, Yueyao Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Pharmacology
Subjects:
Si-Miao-Yong-An
vasa vasorum
atherosclerosis
vulnerable plague
ApoE–/– mice
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.634611/full

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https://www.frontiersin.org/articles/10.3389/fphar.2021.634611/full

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