A Plasmid With Conserved Phage Genes Helps Klebsiella pneumoniae Defend Against the Invasion of Transferable DNA Elements at the Cost of Reduced Virulence

Klebsiella pneumoniae exhibits extensive phenotypic and genetic diversity. Higher plasmid loads in the cell were supposed to play an key role in its genome diversity. Although some plasmids are widely distributed in Kp populations, they are poorly recognized. A plasmid named p2 in strain Kp1604 was...

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Bibliographic Details
Main Authors: Mufeng Cai, Bingchun Pu, Yue Wang, Lin Lv, Chunyu Jiang, Xiaomei Fu, Yan Zhang, Wei Zhao, Ke Dong, Yi Yang, Yangming Liu, Yalu Wei, Zhengyue Zhang, Jianhui Li, Xiaokui Guo, Chang Liu, Jinhong Qin
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-03-01
Series:Frontiers in Microbiology
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Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2022.827545/full