Leishmanicidal Activity of Guanidine Derivatives against <i>Leishmania infantum</i>

Leishmanicidal Activity of Guanidine Derivatives against <i>Leishmania infantum</i>

Leishmaniasis is a neglected tropical infectious disease with thousands of cases annually; it is of great concern to global health, particularly the most severe form, visceral leishmaniasis. Visceral leishmaniasis treatments are minimal and have severe adverse effects. As guanidine-bearing compounds...

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Bibliographic Details
Main Authors: Fernanda Silva Almeida, Vitor Partite Moreira, Edson dos Santos Silva, Leonardo Lima Cardoso, Pedro Henrique de Sousa Palmeira, Luiz Henrique Agra Cavalcante-Silva, Demétrius A. M. de Araújo, Ian P. G. do Amaral, Eduardo René Pérez González, Tatjana S. L. Keesen
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Tropical Medicine and Infectious Disease
Subjects:
Leishmaniasis
anti-leishmanial activity
guanidine compounds
cell death
apoptosis
nitrite production
Online Access:https://www.mdpi.com/2414-6366/8/3/141

Internet

https://www.mdpi.com/2414-6366/8/3/141

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