The Agglomeration Mechanism of Phenytoin (Antiepileptic) by a Novel Agglomerated Crystallization Technique

Novel agglomerated crystallization techniques, i.e., neutralization and solvent change, methods, were devised in order to design phenytoin (antiepileptic), crystals so as to be directly compounded during their formulation. The proposed techniques could directly transform the fine precipitated crysta...

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Bibliographic Details
Main Authors: Yoshiaki Kawashima, Tetsurou Handa, Hirofumi Takeuchi, Motonari Okumura
Format: Article
Language:English
Published: Hosokawa Powder Technology Foundation 2014-06-01
Series:KONA Powder and Particle Journal
Online Access:https://www.jstage.jst.go.jp/article/kona/6/0/6_1988012/_pdf/-char/en