Exploring the contributions of two glutamate decarboxylase isozymes in Lactobacillus brevis to acid resistance and γ-aminobutyric acid production

Exploring the contributions of two glutamate decarboxylase isozymes in Lactobacillus brevis to acid resistance and γ-aminobutyric acid production

Abstract Background The glutamate decarboxylase (GAD) system of Lactobacillus brevis involves two isoforms of GAD, GadA and GadB, which catalyze the conversion of L-glutamate to γ-aminobutyric acid (GABA) in a proton-consuming reaction contributing to intracellular pH homeostasis. However, direct ex...

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Bibliographic Details
Main Authors: Changjiang Lyu, Weirui Zhao, Chunlong Peng, Sheng Hu, Hui Fang, Yujiao Hua, Shanjing Yao, Jun Huang, Lehe Mei
Format: Article
Language:English
Published: BMC 2018-11-01
Series:Microbial Cell Factories
Subjects:
Lactobacillus brevis
GAD system
GABA
Acid resistance
Online Access:http://link.springer.com/article/10.1186/s12934-018-1029-1

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http://link.springer.com/article/10.1186/s12934-018-1029-1

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