Seawater fungi-derived compound screening to identify novel small molecules against dengue virus NS5 methyltransferase and NS2B/NS3 protease

Seawater fungi-derived compound screening to identify novel small molecules against dengue virus NS5 methyltransferase and NS2B/NS3 protease

Dengue fever is a virus spread by mosquitoes that has no effective treatment or vaccination. Several dengue cases combined with the current COVID-19 pandemic, exacerbates this problem. Two proteins, NS5 methyltransferase and NS2B/NS3 primary protease complexes, are crucial for dengue viral replicati...

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Bibliographic Details
Main Authors: Mahamudul Hasan, Md. Mukthar Mia, Shahab Uddin Munna, Md. Mowdudul Hasan Talha, Kanon Das
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:Informatics in Medicine Unlocked
Subjects:
Dengue virus
Marine-derived compounds
NS2B/NS3 protease
NS5 methyltransferase
Molecular docking
Target-prediction
Online Access:http://www.sciencedirect.com/science/article/pii/S2352914822000806

Internet

http://www.sciencedirect.com/science/article/pii/S2352914822000806

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