CircSTX6 promotes pancreatic ductal adenocarcinoma progression by sponging miR-449b-5p and interacting with CUL2

Abstract Background circular RNAs (circRNAs) have been reported to play crucial roles in the biology of different cancers. However, little is known about the function of circSTX6 (hsa_circ_0007905) in pancreatic ductal adenocarcinoma (PDAC). Methods circSTX6, a circRNA containing exons 4, 5, 6 and 7...

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Main Authors: Lingdong Meng, Yihan Zhang, Pengfei Wu, Danrui Li, Yichao Lu, Peng Shen, Taoyue Yang, Guodong Shi, Qun Chen, Hao Yuan, Wanli Ge, Yi Miao, Min Tu, Kuirong Jiang
Format: Article
Language:English
Published: BMC 2022-06-01
Series:Molecular Cancer
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Online Access:https://doi.org/10.1186/s12943-022-01599-5