Suppression of miR-330-3p alleviates DSS-induced ulcerative colitis and apoptosis by upregulating the endoplasmic reticulum stress components XBP1

Suppression of miR-330-3p alleviates DSS-induced ulcerative colitis and apoptosis by upregulating the endoplasmic reticulum stress components XBP1

Abstract Background This study aimed to explore the biological activities of miR-330-3p in dextan sulphate sodium (DSS)-induced ulcerative colitis and apoptosis and the direct target of miR-330-3p in this process. HT-29 cells and male C57BL/6 mice were used to examine the function of miR-330-3p in v...

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Bibliographic Details
Main Authors: Qifeng Chen, Xiaoming Fang, Ning Yao, Fang Wu, Biao Xu, Zhengguang Chen
Format: Article
Language:English
Published: BMC 2020-05-01
Series:Hereditas
Subjects:
miR-330-3p
Ulcerative colitis
Apoptosis
Endoplasmic reticulum stress
XBP1
Online Access:http://link.springer.com/article/10.1186/s41065-020-00135-z

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http://link.springer.com/article/10.1186/s41065-020-00135-z

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