The Senescence Markers p16INK4A, p14ARF/p19ARF, and p21 in Organ Development and Homeostasis

It is widely accepted that senescent cells accumulate with aging. They are characterized by replicative arrest and the release of a myriad of factors commonly called the senescence-associated secretory phenotype. Despite the replicative cell cycle arrest, these cells are metabolically active and fun...

Full description

Bibliographic Details
Main Authors: Kay-Dietrich Wagner, Nicole Wagner
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/11/12/1966