Rab32 uses its effector reticulon 3L to trigger autophagic degradation of mitochondria-associated membrane (MAM) proteins

Rab32 uses its effector reticulon 3L to trigger autophagic degradation of mitochondria-associated membrane (MAM) proteins

Abstract Background Rab32 is a small GTPase associated with multiple organelles but is particularly enriched at the endoplasmic reticulum (ER). Here, it controls targeting to mitochondria-ER contacts (MERCs), thus influencing composition of the mitochondria-associated membrane (MAM). Moreover, Rab32...

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Bibliographic Details
Main Authors: Maria Sol Herrera-Cruz, Megan C. Yap, Nasser Tahbaz, Keelie Phillips, Laurel Thomas, Gary Thomas, Thomas Simmen
Format: Article
Language:English
Published: BMC 2021-11-01
Series:Biology Direct
Subjects:
Rab32
Mitochondria-associated membrane (MAM)
Autophagy
ER-phagy
Online Access:https://doi.org/10.1186/s13062-021-00311-9

Internet

https://doi.org/10.1186/s13062-021-00311-9

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