Two Point Mutations in the Glycoprotein of SFTSV Enhance the Propagation Recombinant Vesicular Stomatitis Virus Vectors at Assembly Step

Two Point Mutations in the Glycoprotein of SFTSV Enhance the Propagation Recombinant Vesicular Stomatitis Virus Vectors at Assembly Step

Severe fever with thrombocytopenia syndrome virus (SFTSV) is an emerging tick-borne pathogen for which approved therapeutic drugs or vaccines are not available. We previously developed a recombinant vesicular stomatitis virus-based vaccine candidate (rVSV-SFTSV) by replacing the original glycoprotei...

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Bibliographic Details
Main Authors: Qiang Hu, Yuhang Zhang, Jiafu Jiang, Aihua Zheng
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Viruses
Subjects:
SFTSV
vaccine
vesicular stomatitis virus
mutation
assembly
Online Access:https://www.mdpi.com/1999-4915/15/3/800

Internet

https://www.mdpi.com/1999-4915/15/3/800

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