Lipid‐Free Apolipoprotein A‐I Reduces Progression of Atherosclerosis by Mobilizing Microdomain Cholesterol and Attenuating the Number of CD131 Expressing Cells: Monitoring Cholesterol Homeostasis Using the Cellular Ester to Total Cholesterol Ratio

Lipid‐Free Apolipoprotein A‐I Reduces Progression of Atherosclerosis by Mobilizing Microdomain Cholesterol and Attenuating the Number of CD131 Expressing Cells: Monitoring Cholesterol Homeostasis Using the Cellular Ester to Total Cholesterol Ratio

BackgroundAtherosclerosis is a chronic inflammatory disorder whose development is inversely correlated with high‐density lipoprotein concentration. Current therapies involve pharmaceuticals that significantly elevate plasma high‐density lipoprotein cholesterol concentrations. Our studies were conduc...

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Bibliographic Details
Main Authors: Sushma Kaul, Hao Xu, Manal Zabalawi, Elisa Maruko, Brian E. Fulp, Theresa Bluemn, Kristina L. Brzoza‐Lewis, Mark Gerelus, Ranjuna Weerasekera, Rachel Kallinger, Roland James, Yi (Sherry) Zhang, Michael J. Thomas, Mary G. Sorci‐Thomas
Format: Article
Language:English
Published: Wiley 2016-10-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
apolipoprotein
apolipoprotein A‐I
cholesterol
chronic inflammation
high‐density lipoprotein
inflammation
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.116.004401

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https://www.ahajournals.org/doi/10.1161/JAHA.116.004401

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