Enhancing the solubility and dissolution rate of piperine via preparation of piperine–hydroxypropyl methylcellulose 2910 solid dispersion system using freeze-drying method

Enhancing the solubility and dissolution rate of piperine via preparation of piperine–hydroxypropyl methylcellulose 2910 solid dispersion system using freeze-drying method

Context: Piperine is the main secondary metabolite isolated from the family Piperaceae. This biologically active ingredient has many pharmacological effects, though its low water solubility limits its absorption in gastrointestinal fluid. Aims: To improve piperine’s solubility and dissolution rat...

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Bibliographic Details
Main Authors: Lili Fitriani, Swari Tirtania, Salman Umar, Erizal Zaini
Format: Article
Language:English
Published: GarVal Editorial Ltda. 2024-01-01
Series:Journal of Pharmacy & Pharmacognosy Research
Subjects:
dissolution
freeze drying
hpmc 2910
piperine
solid dispersion
solubility
Online Access:https://jppres.com/jppres/pdf/vol12/jppres23.1734_12.1.175.pdf

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https://jppres.com/jppres/pdf/vol12/jppres23.1734_12.1.175.pdf

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