Tumoral Neuroligin 1 Promotes Cancer–Nerve Interactions and Synergizes with the Glial Cell Line-Derived Neurotrophic Factor

Tumoral Neuroligin 1 Promotes Cancer–Nerve Interactions and Synergizes with the Glial Cell Line-Derived Neurotrophic Factor

Many nervous proteins are expressed in cancer cells. In this report, we asked whether the synaptic protein neuroligin 1 (NLGN1) was expressed by prostatic and pancreatic carcinomas; in addition, given the tendency of these tumors to interact with nerves, we asked whether NLGN1 played a role in this...

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Bibliographic Details
Main Authors: Laura Bizzozero, Margherita Pergolizzi, Davide Pascal, Elena Maldi, Giulia Villari, Jessica Erriquez, Marco Volante, Guido Serini, Caterina Marchiò, Federico Bussolino, Marco Arese
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Cells
Subjects:
tumor–nervous connections
neuroligin 1
glial cell line-derived neurotrophic factor
cofilin
filopodia
Online Access:https://www.mdpi.com/2073-4409/11/2/280

Internet

https://www.mdpi.com/2073-4409/11/2/280

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