Transection of the cervical sympathetic trunk inhibits the progression of pulmonary arterial hypertension via ERK-1/2 Signalling

Abstract Background Abnormal sympathetic hyperactivity has been shown to lead to pulmonary arterial hypertension (PAH) deterioration. The purpose of this study was to examine whether the transection of the cervical sympathetic trunk (TCST) can inhibit the progression of PAH in a monocrotaline (MCT)-...

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Bibliographic Details
Main Authors: Yongpeng Zhao, Rui Xiang, Xin Peng, Qian Dong, Dan Li, Guiquan Yu, Lei Xiao, Shu Qin, Wei Huang
Format: Article
Language:English
Published: BMC 2019-06-01
Series:Respiratory Research
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12931-019-1090-2