Design, Dimerization, and Recombinant Production of MCh-AMP1–Derived Peptide in Escherichia coli and Evaluation of Its Antifungal Activity and Cytotoxicity

Design, Dimerization, and Recombinant Production of MCh-AMP1–Derived Peptide in Escherichia coli and Evaluation of Its Antifungal Activity and Cytotoxicity

Fungal species resistant to current antifungal agents are considered as a serious threat to human health, the dilemma that has dragged attentions toward other sources of antifungals such as antimicrobial peptides (AMPs). In order to improve biological activity of a recently described antifungal pept...

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Bibliographic Details
Main Authors: Sima Sadat Seyedjavadi, Soghra Khani, Jafar Amani, Raheleh Halabian, Mehdi Goudarzi, Hamideh Mahmoodzadeh Hosseini, Ali Eslamifar, Masoomeh Shams-Ghahfarokhi, Abbas Ali Imani Fooladi, Mehdi Razzaghi-Abyaneh
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Fungal Biology
Subjects:
antifungal activity
cytotoxicity
antimicrobial peptide
Aspergillus
Candida
dimeric antifungal peptides
Online Access:https://www.frontiersin.org/articles/10.3389/ffunb.2021.638595/full

Internet

https://www.frontiersin.org/articles/10.3389/ffunb.2021.638595/full

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