Sex differences in metabolic phenotype and hypothalamic inflammation in the 3xTg-AD mouse model of Alzheimer’s disease

Sex differences in metabolic phenotype and hypothalamic inflammation in the 3xTg-AD mouse model of Alzheimer’s disease

Abstract Background Alzheimer’s disease (AD) is notably associated with cognitive decline resulting from impaired function of hippocampal and cortical areas; however, several other domains and corresponding brain regions are affected. One such brain region is the hypothalamus, shown to atrophy and d...

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Bibliographic Details
Main Authors: Lisa S. Robison, Olivia J. Gannon, Abigail E. Salinero, Charly Abi-Ghanem, Richard D. Kelly, David A. Riccio, Febronia M. Mansour, Kristen L. Zuloaga
Format: Article
Language:English
Published: BMC 2023-08-01
Series:Biology of Sex Differences
Subjects:
Sex
Gender
Alzheimer’s disease
Inflammation
Hypothalamus
Metabolic
Online Access:https://doi.org/10.1186/s13293-023-00536-5

Internet

https://doi.org/10.1186/s13293-023-00536-5

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