In vitro cytotoxicity of Withania somnifera (L.) roots and fruits on oral squamous cell carcinoma cell lines: a study supported by flow cytometry, spectral, and computational investigations

In vitro cytotoxicity of Withania somnifera (L.) roots and fruits on oral squamous cell carcinoma cell lines: a study supported by flow cytometry, spectral, and computational investigations

Oral cancer is a severe health problem that accounts for an alarmingly high number of fatalities worldwide. Withania somnifera (L.) Dunal has been extensively studied against various tumor cell lines from different body organs, rarely from the oral cavity. We thus investigated the cytotoxicity of W....

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Bibliographic Details
Main Authors: Ahmed Abdullah Al Awadh, Hiroshi Sakagami, Shigeru Amano, Ahmed M. Sayed, Mohamed E. Abouelela, Abdulaziz Hassan Alhasaniah, Nayef Aldabaan, Mohamed S. Refaey, Reda A. Abdelhamid, Heba M. A. Khalil, Dalia I. Hamdan, El-Shaymaa Abdel-Sattar, Mohamed A. A. Orabi
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-01-01
Series:Frontiers in Pharmacology
Subjects:
Withania somnifera
oral cancer
flow cytometry
UHPLC MS/MS
CDK2
BRD3
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2024.1325272/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2024.1325272/full

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