Genetic Background Underlying 5-HT<sub>1A</sub> Receptor Functioning Affects the Response to Fluoxetine

Genetic Background Underlying 5-HT<sub>1A</sub> Receptor Functioning Affects the Response to Fluoxetine

The influence of genetic background on sensitivity to drugs represents a topical problem of personalized medicine. Here, we investigated the effect of chronic (20 mg/kg, 14 days, i.p.) antidepressant fluoxetine treatment on recombinant B6-M76C mice, differed from control B6-M76B mice by CBA-derived...

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Bibliographic Details
Main Authors: Elena M. Kondaurova, Alexander Ya. Rodnyy, Tatiana V. Ilchibaeva, Anton S. Tsybko, Dmitry V. Eremin, Yegor V. Antonov, Nina K. Popova, Vladimir S. Naumenko
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:International Journal of Molecular Sciences
Subjects:
SSRI
fluoxetine
antidepressants resistance
5-HT<sub>1A</sub> receptor
mice
serotonin
Online Access:https://www.mdpi.com/1422-0067/21/22/8784

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https://www.mdpi.com/1422-0067/21/22/8784

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