Influenza A Virus H7 nanobody recognizes a conserved immunodominant epitope on hemagglutinin head and confers heterosubtypic protection

Abstract Influenza remains a persistent global health challenge, largely due to the virus’ continuous antigenic drift and occasional shift, which impede the development of a universal vaccine. To address this, the identification of broadly neutralizing antibodies and their epitopes is crucial. Nanob...

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Bibliographic Details
Main Authors: Zhao-Shan Chen, Hsiang-Chi Huang, Xiangkun Wang, Karin Schön, Yane Jia, Michael Lebens, Danica F. Besavilla, Janarthan R. Murti, Yanhong Ji, Aishe A. Sarshad, Guohua Deng, Qiyun Zhu, Davide Angeletti
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-55193-y