Assessing equivalent and inverse change in genes between diverse experiments

Assessing equivalent and inverse change in genes between diverse experiments

Background: It is important to identify when two exposures impact a molecular marker (e.g., a gene’s expression) in similar ways, for example, to learn that a new drug has a similar effect to an existing drug. Currently, statistically robust approaches for making comparisons of equivalence of effect...

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Bibliographic Details
Main Authors: Lisa Neums, Devin C. Koestler, Qing Xia, Jinxiang Hu, Shachi Patel, Shelby Bell-Glenn, Dong Pei, Bo Zhang, Samuel Boyd, Prabhakar Chalise, Jeffrey A. Thompson
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Bioinformatics
Subjects:
differential gene expression
equivalence test
study comparison
diverse experiments
molecular marker
Online Access:https://www.frontiersin.org/articles/10.3389/fbinf.2022.893032/full

Internet

https://www.frontiersin.org/articles/10.3389/fbinf.2022.893032/full

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