A slow-releasing donor of hydrogen sulfide inhibits neuronal cell death via anti-PANoptosis in rats with spinal cord ischemia‒reperfusion injury

A slow-releasing donor of hydrogen sulfide inhibits neuronal cell death via anti-PANoptosis in rats with spinal cord ischemia‒reperfusion injury

Abstract Background Spinal cord ischemia‒reperfusion injury (SCIRI) can lead to paraplegia, which leads to permanent motor function loss. It is a disastrous complication of surgery and causes tremendous socioeconomic burden. However, effective treatments for SCIRI are still lacking. PANoptosis consi...

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Bibliographic Details
Main Authors: Lei Xie, Hang Wu, Qiuping He, Weipeng Shi, Jing Zhang, Xiao Xiao, Tengbo Yu
Format: Article
Language:English
Published: BMC 2024-01-01
Series:Cell Communication and Signaling
Subjects:
PANoptosis
Hydrogen sulfide
Inflammation
Microglia/macrophage
Spinal cord ischemia‒reperfusion injury
Online Access:https://doi.org/10.1186/s12964-023-01457-x

Internet

https://doi.org/10.1186/s12964-023-01457-x

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