Discovery of circulating miRNAs as biomarkers of chronic Chagas heart disease via a small RNA-Seq approach

Abstract Chagas disease affects approximately 7 million people worldwide in Latin America and is a neglected tropical disease. Twenty to thirty percent of chronically infected patients develop chronic Chagas cardiomyopathy decades after acute infection. Identifying biomarkers of Chagas disease progr...

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Main Authors: Silvina R. Villar, Alfonso Herreros-Cabello, Francisco Callejas-Hernández, María C. Maza, Javier del Moral-Salmoral, Mario Gómez-Montes, Héctor O. Rodríguez-Angulo, Irene Carrillo, Miguel Górgolas, Pau Bosch-Nicolau, Israel Molina, José A. Pérez-Molina, Begoña Monge-Maillo, Oscar A. Bottasso, Juan Beloscar, Ana R. Pérez, Manuel Fresno, Núria Gironès
Format: Article
Language:English
Published: Nature Portfolio 2024-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-024-51487-9